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1

Solubility of hydrophobic compounds in water–cosolvent mixtures: Relation of solubility with water–cosolvent interactions

Yasuhiro Miyako, Yinyan Zhao, Kazuo Takeshima, Takahiro Kataoka, Tetsurou Handa, Rodolfo Pinal

Journal:

Journal of Pharmaceutical Sciences

Year:

2010

Language:

english

File:

PDF, 177 KB

english, 2010

2

The preparation of functional microspheres of pharmaceuticals with acrylic polymer (Eudragit) by a novel spherical crystallization technique.

KAWASHIMA, Yoshiaki, NIWA, Toshiyuki, HANDA, Tetsurou, TAKEUCHI, Hirofumi

Journal:

Journal of the Society of Powder Technology Japan

Year:

1987

File:

PDF, 1.94 MB

1987

3

Effect of polymer type on the dissolution profile of amorphous solid dispersions containing felodipine

Hajime Konno, Tetsurou Handa, David E. Alonzo, Lynne S. Taylor

Journal:

European Journal of Pharmaceutics and Biopharmaceutics

Year:

2008

Language:

english

File:

PDF, 257 KB

english, 2008

4

Adsorption of fluorocarbon and hydrocarbon surfactants to air-water, hexane-water and perfluorohexane-water interfaces. Relative affinities and fluorocarbon-hydrocarbon nonideality effects

Mukerjee, Pasupati, Handa, Tetsurou

Journal:

Journal of Physical Chemistry

Year:

1981

Language:

english

File:

PDF, 803 KB

english, 1981

5

Effects of Cholesterol and Cholesteryl Oleate on Lipolysis and Liver Uptake of Triglyceride/Phosphatidylcholine Emulsions in Rats

Tetsurou Handa, Yuko Eguchi, Koichiro Miyajima

Journal:

Pharmaceutical Research

Year:

1994

File:

PDF, 850 KB

1994

6

Effects of an Amphipathic α-Helical Peptide on Lateral Pressure and Water Penetration in Phosphatidylcholine and Monoolein Mixed Membranes

Kamo, Tomoari, Nakano, Minoru, Kuroda, Yoshihiro, Handa, Tetsurou

Journal:

Journal of Physical Chemistry B

Year:

2006

Language:

english

File:

PDF, 90 KB

english, 2006

7

Chylomicron remnant model emulsions induce intracellular cholesterol accumulation and cell death due to lysosomal destabilization

Wakita, Kyoko, Morita, Shin-ya, Okamoto, Naoko, Takata, Eriko, Handa, Tetsurou, Nakano, Minoru

Journal:

Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids

Year:

2015

Language:

english

File:

PDF, 1.17 MB

english, 2015

8

Microenvironment around thiacarbocyanine dyes in lysolecithin micelles, surfactant micelles and lecithin liposomal membranes.

NAKAGAKI, MASAYUKI, KOMATSU, HIROAKI, HANDA, TETSUROU

Journal:

CHEMICAL & PHARMACEUTICAL BULLETIN

Year:

1986

File:

PDF, 769 KB

1986

9

Spherical solid dispersion containing amorphous tolbutamide embedded in enteric coating polymers or colloidal silica prepared by spray-drying technique.

TAKEUCHI, HIROFUMI, HANDA, TETSUROU, KAWASHIMA, YOSHIAKI

Journal:

CHEMICAL & PHARMACEUTICAL BULLETIN

Year:

1987

Language:

english

File:

PDF, 4.81 MB

english, 1987

10

Novel action of apolipoprotein E (ApoE): ApoE isoform specifically inhibits lipid-particle-mediated cholesterol release from neurons

Jian-Sheng Gong, Shin-ya Morita, Mariko Kobayashi, Tetsurou Handa, Shinobu C Fujita, Katsuhiko Yanagisawa, Makoto Michikawa

Journal:

Molecular Neurodegeneration

Year:

2007

Language:

english

File:

PDF, 468 KB

english, 2007

11

Lateral pressure change on phase transitions of phosphatidylcholine/diolein mixed membranes

Kamo, Tomoari, Handa, Tetsurou, Nakano, Minoru

Journal:

Colloids and Surfaces B: Biointerfaces

Year:

2013

Language:

english

File:

PDF, 291 KB

english, 2013

12

Quantitative analysis of hemolytic action of lysophosphatidylcholines in vitro: Effect of acyl chain structure.

MATSUZAKI, KATSUMI, HANDA, TETSUROU, MIYAJIMA, KOICHIRO, MIKURA, YASUSHI, SHIMIZU, HISAYOSHI, TOGUCHI, HAJIME

Journal:

CHEMICAL & PHARMACEUTICAL BULLETIN

Year:

1988

Language:

english

File:

PDF, 1.14 MB

english, 1988

13

Lyophilized liposomes prepared by a modified reversed-phase evaporation method.

HANDA, TETSUROU, TAKEUCHI, HIROFUMI, OHOKUBO, YUICHI, KAWASHIMA, YOSHIAKI

Journal:

CHEMICAL & PHARMACEUTICAL BULLETIN

Year:

1987

Language:

english

File:

PDF, 1.09 MB

english, 1987

14

Nano World Created by Self-organization

UENO, Masaharu, HANDA, Tetsurou

Journal:

YAKUGAKU ZASSHI

Year:

2008

File:

PDF, 140 KB

2008

15

Thermal Studies on Interactions between Gramicidin S and Phospholipid Membranes

NAKAGAKI, MASAYUKI, HANDA, TETSUROU, SEHARA, CHIKAKO

Journal:

YAKUGAKU ZASSHI

Year:

1981

File:

PDF, 683 KB

1981

16

Surface composition regulates clearance from plasma and triolein lipolysis of lipid emulsions

Itaru Arimoto, Chizuko Matsumoto, Masafumi Tanaka, Keiichirou Okuhira, Hiroyuki Saito, Tetsurou Handa

Journal:

Year:

1998

Language:

english

File:

PDF, 486 KB

english, 1998

17

A fluorescent probing study on microenvironments in bile salt micelles and bile salt/phosphatidylcholine mixtures in the absence or presence of cholesterol

Katsumi Matsuzaki, Isao Yokoyama, Hiroaki Komatsu, Tetsurou Handa, Koichiro Miyajima

Journal:

Biochimica et Biophysica Acta (BBA) - Biomembranes

Year:

1989

Language:

english

File:

PDF, 424 KB

english, 1989

18

13 C NMR Method for the Determination of Peptide and Protein Binding Sites in Lipid Bilayers and Emulsions

Okamura, Emiko, Kimura, Tomohiro, Nakahara, Masaru, Tanaka, Masafumi, Handa, Tetsurou, Saito, Hiroyuki

Journal:

Journal of Physical Chemistry B

Year:

2001

Language:

english

File:

PDF, 143 KB

english, 2001

19

Effects of lysophosphatidylcholine micelle and phosphatidylcholine liposome on photoreduction of methylviologen

Masayuki Nakagaki, Hiroaki Komatsu, Tetsurou Handa

Journal:

Archives of Biochemistry and Biophysics

Year:

1986

Language:

english

File:

PDF, 680 KB

english, 1986

20

Resonance energy transfer study of peptide–lipid complexes

Galyna Gorbenko, Hiroyuki Saito, Julian Molotkovsky, Masafumi Tanaka, Masashi Egashira, Minoru Nakano, Tetsurou Handa

Journal:

Biophysical Chemistry

Year:

2001

Language:

english

File:

PDF, 186 KB

english, 2001

21

Effects of 1,2-diacylglycerol and cholesterol on the hydrolysis activity of phospholipase D in egg-yolk phosphatidylcholine bilayers

Izumi Yamamoto, Takako Mazumi, Tetsurou Handa, Koichiro Miyajima

Journal:

Biochimica et Biophysica Acta (BBA) - Biomembranes

Year:

1993

Language:

english

File:

PDF, 429 KB

english, 1993

22

Effect of phospholipid composition on discoidal HDL formation

Miyazaki, Masakazu, Tajima, Yoko, Ishihama, Yasushi, Handa, Tetsurou, Nakano, Minoru

Journal:

Biochimica et Biophysica Acta (BBA) - Biomembranes

Year:

2013

Language:

english

File:

PDF, 654 KB

english, 2013

23

Surface Tension of Aqueous Solutions of Disodium Monoalkyl Phosphates and Their Mixtures

Nakagaki, Masayuki, Handa, Tetsurou

Journal:

Bulletin of the Chemical Society of Japan

Year:

1975

File:

PDF, 807 KB

1975

24

Effects of Alkyl Chains of Thiacarbocyanine as the Sensitizer for the Photoreduction of Methylviologen in Micellar Phase

Nakagaki, Masayuki, Komatsu, Hiroaki, Handa, Tetsurou

Journal:

Bulletin of the Chemical Society of Japan

Year:

1985

File:

PDF, 1.12 MB

1985

25

S—shaped adsorption isotherms of surface active electrolytes from aqueous solutions

Masayuki Nakagaki, Tetsurou Handa, Saburo Shimabayashi

Journal:

Journal of Colloid and Interface Science

Year:

1973

Language:

english

File:

PDF, 581 KB

english, 1973

26

Inhibition of autophosphorylation of epidermal growth factor receptor by small peptides in vitro

Mineo Abe, Yoshihiro Kuroda, Munetaka Hirose, Yoshihiko Watanabe, Minoru Nakano, Tetsurou Handa

Journal:

British Journal of Pharmacology

Year:

2006

Language:

english

File:

PDF, 381 KB

english, 2006

27

Enhancement of the dissolution rate of a poorly water-soluble drug (tolbutamide) by a spray-drying solvent deposition method and disintegrants

Takeuchi, Hirofumi, Handa, Tetsurou, Kawashima, YOshiaki

Journal:

Journal of Pharmacy and Pharmacology

Year:

1987

Language:

english

File:

PDF, 653 KB

english, 1987

28

Comparative Study of Fluorescence Anisotropy in Surface Monolayers of Emulsions and Bilayers of Vesicles

Saito, Hiroyuki, Nishiwaki, Kenji, Handa, Tetsurou, Ito, Shinzaburo, Miyajima, Koichiro

Journal:

Year:

1995

Language:

english

File:

PDF, 842 KB

english, 1995

29

Comparative Estimation of the Liposomal Content of Phosphatidylcholine/Triolein Emulsions Using fluorescence Quenching and 1H-NMR Techniques.

KOMATSU, Hiroaki, HANDA, Tetsurou, MIYAJIMA, Koichiro

Journal:

CHEMICAL & PHARMACEUTICAL BULLETIN

Year:

1994

File:

PDF, 782 KB

1994

30

Interactions and structure—organizations of menaquinone-4 and egg yolk phosphatidylcholine mixtures: Formation of bilayer and nonbilayer structures in an aqueous medium

Tetsurou Handa, Yasuyuki Asai, Hiroaki Komatsu, Koichiro Miyajima

Journal:

Journal of Colloid and Interface Science

Year:

1992

Language:

english

File:

PDF, 2.08 MB

english, 1992

31

Synthetic pentapeptides inhibiting autophosphorylation of insulin receptor in a non-ATP-competitive mechanism

Masaki Kato, Mineo Abe, Yoshihiro Kuroda, Munetaka Hirose, Minoru Nakano, Tetsurou Handa

Journal:

Journal of Peptide Science

Year:

2009

Language:

english

File:

PDF, 558 KB

english, 2009

32

Effects of plasma apolipoproteins on lipoprotein lipase-mediated lipolysis of small and large lipid emulsions

Mayumi Yamamoto, Shin-ya Morita, Michiko Kumon, Misa Kawabe, Kazuchika Nishitsuji, Hiroyuki Saito, Aline Vertut-Doı̈, Minoru Nakano, Tetsurou Handa

Journal:

Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids

Year:

2003

Language:

english

File:

PDF, 193 KB

english, 2003

33

Static and Dynamic Properties of Phospholipid Bilayer Nanodiscs

Nakano, Minoru, Fukuda, Masakazu, Kudo, Takayuki, Miyazaki, Masakazu, Wada, Yusuke, Matsuzaki, Naoya, Endo, Hitoshi, Handa, Tetsurou

Journal:

Journal of the American Chemical Society

Year:

2009

Language:

english

File:

PDF, 1.31 MB

english, 2009

34

Effects of EDTA Derivatives on the Photoreduction of Methyl Viologen by a Thiacarbocyanine Sensitizer in a Micellar Solution

Nakagaki, Masayuki, Komatsu, Hiroaki, Tanaka, Hiromi, Handa, Tetsurou

Journal:

Bulletin of the Chemical Society of Japan

Year:

1986

File:

PDF, 898 KB

1986

35

Thermal Studies on Polymorphisms of Phospholipids. II. Polymorphism of L-Dipalmitoyl Phosphatidylethanolamine-Water Mixtures

NAKAGAKI, MASAYUKI, HANDA, TETSUROU, OHASHI, KAYOKO

Journal:

YAKUGAKU ZASSHI

Year:

1979

File:

PDF, 677 KB

1979

36

Equilibrium among Lipid Molecular Assemblies and Their Surface Microenvironment

HANDA, Tetsurou

Journal:

YAKUGAKU ZASSHI

Year:

1991

File:

PDF, 1.93 MB

1991

37

Development of manufacturing method for rapidly disintegrating oral tablets using the crystalline transition of amorphous sucrose

Masaaki Sugimoto, Shinji Narisawa, Koji Matsubara, Hiroyuki Yoshino, Minoru Nakano, Tetsurou Handa

Journal:

International Journal of Pharmaceutics

Year:

2006

Language:

english

File:

PDF, 332 KB

english, 2006

38

Formation of ceramide-enriched domains in lipid particles enhances the binding of apolipoprotein E

Shin-ya Morita, Minoru Nakano, Atsushi Sakurai, Yuko Deharu, Aline Vertut-Doï, Tetsurou Handa

Journal:

Year:

2005

Language:

english

File:

PDF, 308 KB

english, 2005

39

Nonlamellar Liquid Crystalline Phases and Their Particle Formation in the Egg Yolk Phosphatidylcholine/Diolein System

Kamo, Tomoari, Nakano, Minoru, Leesajakul, Warunee, Sugita, Atsuhiko, Matsuoka, Hideki, Handa, Tetsurou

Journal:

Year:

2003

Language:

english

File:

PDF, 73 KB

english, 2003

40

Estimation of critical micelle concentrations of lysolecithins with fluorescent probes.

NAKAGAKI, MASAYUKI, KOMATSU, HIROAKI, HANDA, TETSUROU

Journal:

CHEMICAL & PHARMACEUTICAL BULLETIN

Year:

1986

File:

PDF, 697 KB

1986

41

The effects of surfactants on the water dispersibility of spray dried vitamin-E powders.

KAWASHIMA, Yoshiaki, TAKEUCHI, Hirofumi, SASAKI, Hideto, HANDA, Tetsurou, MIYAKE, Yasuo, KAYANO, Masanori, UESUGI, Keizou

Journal:

Journal of the Society of Powder Technology Japan

Year:

1988

File:

PDF, 2.11 MB

1988

42

Interaction of differently oriented lipids in monolayer: mixed monolayers of 16-(9-anthroyloxy)palmitic acid with phosphatidylcholine and cholesterol

Nakagaki, Masayuki, Tomita, Keiko, Handa, Tetsurou

Journal:

Year:

1985

Language:

english

File:

PDF, 697 KB

english, 1985

43

Effect of the solubilized state of tetraphenylporphyrin as a photosensitizer on the photooxidation of methyl orange in sodium dodecyl sulfate solution.

NAKAGAKI, MASAYUKI, INOUE, KAZUHIRO, KOMATSU, HIROAKI, HANDA, TETSUROU, MIYAJIMA, KOICHIRO

Journal:

CHEMICAL & PHARMACEUTICAL BULLETIN

Year:

1988

File:

PDF, 754 KB

1988

44

Effects of polyethylene glycol on the size of agglomerated crystals of phenytoin prepared by the spherical crystallization technique.

KAWASHIMA, YOSHIAKI, HANDA, TETSUROU, TAKEUCHI, HIROFUMI, OKUMURA, MOTONARI

Journal:

CHEMICAL & PHARMACEUTICAL BULLETIN

Year:

1986

File:

PDF, 823 KB

1986

45

Generation of Formaldehyde by Pharmaceutical Excipients and Its Absorption by Meglumine

Fujita, Megumi, Ueda, Tomohiko, Handa, Tetsurou

Journal:

CHEMICAL & PHARMACEUTICAL BULLETIN

Year:

2009

Language:

english

File:

PDF, 198 KB

english, 2009

46

Interaction of cubosomes with plasma components resulting in the destabilization of cubosomes in plasma

Warunee Leesajakul, Minoru Nakano, Atsuhiko Taniguchi, Tetsurou Handa

Journal:

Colloids and Surfaces B: Biointerfaces

Year:

2004

Language:

english

File:

PDF, 130 KB

english, 2004

47

Effects of the acyl chain composition of phosphatidylcholines on the stability of freeze-dried small liposomes in the presence of maltose

Hiroaki Komatsu, Hiroyuki Saito, Satoshi Okada, Masafumi Tanaka, Masashi Egashira, Tetsurou Handa

Journal:

Chemistry and Physics of Lipids

Year:

2001

Language:

english

File:

PDF, 121 KB

english, 2001

48

Control of phospholipid flip-flop by transmembrane peptides

Kaihara, Masanori, Nakao, Hiroyuki, Yokoyama, Hirokazu, Endo, Hitoshi, Ishihama, Yasushi, Handa, Tetsurou, Nakano, Minoru

Journal:

Chemical Physics

Year:

2013

Language:

english

File:

PDF, 752 KB

english, 2013

49

Anomeric Effects on the Stability of Bilayers of Galactosylphytoceramides and on the Interaction with Phospholipids

Nakano, Minoru, Inoue, Rui, Koda, Motoko, Baba, Teruhiko, Matsunaga, Hiroki, Natori, Takenori, Handa, Tetsurou

Journal:

Year:

2000

Language:

english

File:

PDF, 136 KB

english, 2000

50

The Penetration of Disodium Hexadecyl Phosphate to the Monolayers of Cholesterol and its Esters from the Underlyning Aqueous Solutions

Nakagaki, Masayuki, Handa, Tetsurou

Journal:

Bulletin of the Chemical Society of Japan

Year:

1976

File:

PDF, 803 KB

1976

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